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patients taking verapamil (calan) and digoxin (lanoxin) should have digoxin (lanoxin) levels monitored closely because of an increased risk of toxicity.

Sagot :

The above statement "patients taking verapamil and digoxin levels monitored closely because of an increased risk of toxicity" is true.

Why does verapamil cause digoxin toxicity?

Verapamil is known to decrease the renal tubular elimination of digoxin. Because of increase in the digoxin blood plasma concentrations lead to adverse drug reactions and cause digoxin toxicity.

Verapamil increases serum digoxin concentration by reducing renal and nonrenal digoxin clearance.

Digoxin causes the increase in intracellular sodium that will drive calcium inside the heart, and this causes the increase in contractility. It is used to treat congestive heart failure and heart rhythm problem called atrial fibrillation.

Both verapamil and digoxin depress myocardial conduction. If any combinations of these drugs must be used the patient should be monitored very closely and appropriate dose adjustments must be made.  Verapamil has also been associated with serious respiratory depression when given with general anesthetics or as an adjunct to anesthesia.

Hence, patients taking verapamil (calan) and digoxin (lanoxin) should have digoxin levels monitored closely because of increased risk of toxicity.

Learn more about verapamil drug from the link given below:

https://brainly.com/question/8678886

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