Pyruvate is a byproduct of glycolysis.The oxidative deacetylation of pyruvate to produce carbon dioxide and acetyl CoA is catalyzed by the multienzyme complex dopamine dehydrogenase complex (PDH complex).Pyruvate + CoA + NAD+ ----> Acetate CoA + NADH + H++ CO2. Acetyl CoA ———- Citric Acid Cycle is the general equation for the reaction.
How is acetyl CoA produced from pyruvate?
Coenzyme A is joined with the oxidized two-carbon acetyl group to generate acetyl CoA.
What enzyme is in charge of turning pyruvate into acetyl CoA?
The pyruvate dehydrogenase (PDH) enzyme, which is a component of the multienzyme PDC and is frequently described to as a "gatekeeper" in the oxidation of carbohydrates, catalyzes the physiologically irreversible conversion of pyruvate to acetyl-CoA.
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