In order for the NMDA receptor to fully open and allow an influx of calcium, both glutamate and glycine must bind to cause a depolarization of the cell that will ultimately displace which ion? Is the NMDA receptor an ionotropic or metabotropic receptor?



a.

Sodium - ionotropic



b.

Sodium - metabotropic



c.

Magnesium - metabotropic



d.

Magnesium - ionotropic



With second-generation antipsychotics, what is the main side effect that requires frequent monitoring?



A.

Metabolic Syndrome



B.

Extra-pyramidal symptoms



C.

Parkinsonism



D.

Dystonia



Choose the appropriate pair regarding acetylcholine receptors.



a.

Nicotinic - ion; muscarinic - ion



b.

Nicotinic - G-protein; muscarinic - ion



c.

Nicotinic - G-protein; muscarinic - G-protein



d.

Nicotinic - ion; muscarinic - G-protein



e.

None of the above is correc

Which disease state of a non-adherent patient is at greater risk for substance use, violence, and victimization as well as worse overall quality of life?



a.

Parkinson's Disease



b.

Multiple Sclerosis



c.

Schizophrenia



d.

Major depressive disorder

Choose the appropriate statement regarding lamotrigine dosing.



A.

If adding carbamazepine decrease lamotrigine dose



B.

If adding valproic acid decrease lamotrigine dose



C.

If adding carbamazepine no dose change is needed



D.

If adding valproic acid no dose change is needed



Choose the correct option regarding the major classes of GABA receptors and the ions involved in inhibition of the neurotransmitter pathway



a.

GABAA - ionotropic - calcium and potassium



b.

GABAB - ionotropic - chloride



c.

GABAB - metabotropic - Calcium and potassium



d.

GABAA - metabotropic - chloride



Which statement is TRUE regarding the use of selective serotonin reuptake inhibitors (SSRI)/serotonin-norepinephrine reuptake inhibitors (SNRI) in patients with Generalized Anxiety Disorder?



A.

Symptom remission is expected within 1 week.



B.

Symptoms may worsen initially with SSRI treatment.



C.

They are considered second-line therapy.



D.

Start at the usual starting dose that is consistent with depression treatment.



Which atypical antipsychotic(s) require a meal for better absorption?

i. Quetiapine

ii. Ziprasidone

iii. Asenapine

iv. Olanzapine

v. Lurasidone



A.

I and V



B.

II and V



C.

III and V



D.

V only