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Causes of muscle fatigue Exercise and other physical activity are a common cause of muscle fatigue. Changes in Na + or K+ concentration Changes in Na+ or K+ concentrations .Insufficient Ca2+ and neuromuscular dysfunction.

Muscle fatigue is the reduction of the muscle's ability to produce energy. It may be due to vigorous exercise but poor fatigue may cause obstruction or interference at various levels of muscle contraction. In vigorous aerobic exercise, increased hydrogen ions lower the pH to below 6.5, causing severe fatigue. If magnesium deficiency is not treated, things can get worse. Severe magnesium deficiency can cause: Heart failure. Death and suffering.

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