Metastatic cancer cells:
have lost their adhesion to the extracellular matrix, freeing them from the original tumor.only need to cross a single layer of capillary endothelial cells to form tumors at distant sites.become malignant when they grow rapidly.are able to leave the tumor where they originated and travel to distant locations to begin new tumors at distant sites.All of these choices are correct.are able to leave the tumor where they originated and travel to distant locations to begin new tumors at distant sites.

Question

06-12-2022
Biology

Answered

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Metastatic cancer cells:
have lost their adhesion to the extracellular matrix, freeing them from the original tumor.only need to cross a single layer of capillary endothelial cells to form tumors at distant sites.become malignant when they grow rapidly.are able to leave the tumor where they originated and travel to distant locations to begin new tumors at distant sites.All of these choices are correct.are able to leave the tumor where they originated and travel to distant locations to begin new tumors at distant sites.

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fawadmohd fawadmohd · Answer 1 · 2022-12-08T13:20:21-05:00

yes, Metastatic cancer cells are able to leave the tumor where they originated and travel to distant locations to begin new tumors at distant sites.

The three basic steps of invasion, intravasation, and extravasation can be used to broadly classify the metastatic cascade. Malignant tumor cells can separate from the primary tumor mass due to a loss of cell-cell adhesion capacity, and this separation opens the door for the cells to invade the stroma around the primary tumor through modifications in cell-matrix interactions. In addition to the expression or suppression of proteins involved in the regulation of motility and migration, this involves the secretion of substances that break down the extracellular matrix and basement membrane.

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