compared to cells with normal gtp, what would result if a g protein-coupled receptor was activated but treated with a nonhydrolyzable version of gtp (a form of gtp that cannot be converted to gdp) that was taken up by the cells?

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06-12-2022
Biology

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compared to cells with normal gtp, what would result if a g protein-coupled receptor was activated but treated with a nonhydrolyzable version of gtp (a form of gtp that cannot be converted to gdp) that was taken up by the cells?

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Neetoo Neetoo · Answer 1 · 2022-12-08T09:54:25-05:00

The result if a g protein-coupled receptor was activated but treated with a nonhydrolyzable version of gtp that was taken up by the cells will be higher cAMP and higher protein kinase A activity.

A transmembrane helical protein called a G- protein-coupled receptor (GPCR) is physically connected to a smaller G protein at the cytosolic location. GTPase switch proteins include G-protein. Alpha, beta, & gamma are the three subunits that make it up. A catalytic subunit is the alpha subunit. Guanine nucleotides like guanosine diphosphate (GDP) and guanosine triphosphate interact with it (GTP). The alpha subunit is inhibited by the beta-gamma complex. If a g protein-coupled receptor was activated but treated with a nonhydrolyzable version of gtp the result will be higher cAMP and higher protein kinase A activity.

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