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Sagot :
5' A C G U U A G G 3' This represents the primer sequence. The base sequence below is present at the DNA site where the strand opens to form a replication fork.
To synthesize DNA, double-stranded DNA is unwound by a DNA helicase in front of the polymerase to form a replication fork containing two single-stranded templates. The replication process copies one DNA double helix into her two DNA helices, which split into daughter cells at mitosis. At the fork, her two main activities take place: DNA unwinding and DNA synthesis. Through the helicase enzyme complex, RF unwinds previously unreplicated DNA. Since DNA replication in eukaryotic cells must be coupled with DNA repair and assembly of DNA into chromatin, replication fork proteins are responsible for maintaining DNA replication fidelity, coordinating replication and cell cycle progression, and chromatin
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