Prenatal exposure to diethylstilbestrol (DES) can result in Vaginal cancer.
Vulvar cancer is a condition in which malignant (cancer) cells develop in the vulva. Age and HPV infection are both risk factors for Vulvar cancer. Pain or abnormal vulvar bleeding are signs and symptoms of Vulvar cancer.
Vulvar cancer is a type of cancer that affects the vulva, which is the outer portion of the female genitals. It usually affects the labia majora. The labia minora and vaginal glands are less commonly affected. A lump, itchiness, changes in the skin, or bleeding from the vulva are all symptoms.
DES has been identified as a transplacental chemical carcinogen; a small percentage of the daughters of DES-using mothers developed vaginal adenocarcinomas.
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