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What is the main difference between the humoral immune response (HIR) and cell-mediated immune responses (CMIR)?

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Greenleafable
the main difference between the humoral immune response (HIR) and cell-mediated immune responses (CMIR) is : HIR provides immunity against antigens and pathogens in body fluids, while CMIR provides immunity against the body’s own cells that have either become cancerous or infected.
 B. HIR provides immunity against antigens and pathogens in body fluids, while CMIR provides immunity against the body’s own cells that have either become cancerous or infected.
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