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What was a major cause for the shift in European
trade from the Mediterranean Sea to the Atlantic
Ocean during the late 140os?
(1) Ottoman Turks seized control of
Constantinople.
(2) The Ming dynasty authorized Zheng He to
make long-distance voyages.
(3) The Tokugawa shogunate adopted an
isolationist policy.
(4) Christian crusaders captured Jerusalem.

Sagot :

"(1) Ottoman Turks seized control of Constantinople" would be the best option as to a major cause for the shift in European trade from the Mediterranean Sea to the Atlantic Ocean during the late 1400s.