In the 18th century, Carolus Linnaeus classified
organisms based on their structural similarities.
Modern classification determines relationships
more accurately because it is based on genetic
and other biochemical similarities. This change
in classification method best illustrates that
(1) multiple trials are required to increase the
validity of a scientific explanation
(2) scientific explanations are subject to the
ethical view of the scientist proposing them
(3) peer review is required to validate the results
of scientific investigations
(4) all scientific explanations are tentative and
subject to change and improvement