The BRCA1 protein is coded for at position 5677 on chromosome 17. Mutations in the BRCA1 gene are associated with elevated risk of breast cancer. BCPR is another gene on chromosome 17. BCPR codes for tp53, a tumor-suppressor protein. When functioning properly, tp53 reduces the chances of tumor growth for multiple cancers, including breast cancer. For simplicity, we will call healthy BRCA1 alleles 1 and malfunctioning BRCA1 alleles 1-. We will call healthy BCPR alleles 2 and malfunctioning BCPR alleles 2-. Alyssa and Vikas have a child named Connor. Connor is a carrier for the BRCA1 malfunctioning allele, giving him a BRCA1 genotype of 1 1-. He is also a carrier for the BCPR malfunctioning allele, giving him a BCPR genotype of 2 2-.

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02-06-2024
Biology

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The BRCA1 protein is coded for at position 5677 on chromosome 17. Mutations in the BRCA1 gene are associated with elevated risk of breast cancer. BCPR is another gene on chromosome 17. BCPR codes for tp53, a tumor-suppressor protein. When functioning properly, tp53 reduces the chances of tumor growth for multiple cancers, including breast cancer. For simplicity, we will call healthy BRCA1 alleles 1 and malfunctioning BRCA1 alleles 1-. We will call healthy BCPR alleles 2 and malfunctioning BCPR alleles 2-. Alyssa and Vikas have a child named Connor. Connor is a carrier for the BRCA1 malfunctioning allele, giving him a BRCA1 genotype of 1 1-. He is also a carrier for the BCPR malfunctioning allele, giving him a BCPR genotype of 2 2-.

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