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You sequenced a tumor genome and a healthy tissue genome. You find that there are half as many reads mapping to a region on chromosome 13 for the tumor sample versus the healthy cell sample. Which of the following is most consistent with this observation?
a. The tumor has a duplication in chromosome 13
b. The tumor has an inversion in chromosome 13
c. The tumor has a translocation between chromosome 13 and another chromosome
d. The tumor has a deletion in chromosome 13
e. None of the answers is correct; this must be an experimental error