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Describe the differences that you observed between a
normal pancreatic islet and a pancreatic islet of a person
with diabetes mellitus.


Sagot :

Final answer:

Differences between normal pancreatic islets and those in diabetes mellitus including cell composition, insulin production, and histological changes.


Explanation:

Pancreatic Islets in Diabetes Mellitus vs. Normal Pancreatic Islets:

  1. Cell Composition: In a normal pancreatic islet, there is a balance of different cell types like alpha, beta, and delta cells, while in a diabetic pancreas, beta cells that produce insulin are selectively destroyed in type 1 diabetes.
  2. Insulin Production: Normal islets release insulin in response to glucose levels, providing precise control. Diabetic islets lack this regulation, resulting in fluctuating blood sugar levels.
  3. Histological Changes: Diabetic islets exhibit structural abnormalities such as reduced size and altered cell distribution compared to normal islets.

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