Westonci.ca is the Q&A platform that connects you with experts who provide accurate and detailed answers. Discover a wealth of knowledge from professionals across various disciplines on our user-friendly Q&A platform. Get precise and detailed answers to your questions from a knowledgeable community of experts on our Q&A platform.

A patient presents to the emergency department with aspirin overdose. The new prescriber reads that aspirin is renally eliminated and wants to expedite the process. Based on your knowledge of pH partitioning and pharmacokinetics , what would you suggest to increase excretion of aspirin through the urine?
Group of answer choices
A. The patient should be administered ascorbic acid to make the urine more acidic. This will decrease ionization of aspirin and keep it trapped in the urine for elimination
B. The patient should be administered ascorbic acid to make the urine more acidic. This will increase ionization of aspirin and keep it trapped in the urine for elimination
C. The patient should be administered Sodium bicarbonate to make the urine more alkaline. This will decrease ionization of aspirin and keep it trapped in the urine for elimination
D. The patient should be administered Sodium bicarbonate to make the urine more alkaline. This will increase ionization of aspirin and keep it trapped in the urine for elimination