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Why does sickle cell anemia remain more prevalent in Sub-Saharan Africa than in the rest of the world?
A. The prevalence of malaria in Sub-Saharan Africa provided a selective advantage to individuals who were heterozygous.
B. People of African ancestry are genetically predisposed to carry the sickle cell allele.
C. Infection with malaria provides a selective disadvantage to individuals who are heterozygous for the sickle cell allele.
D. Reduced access to medical facilities predisposes Sub-Saharan Africans to an increased chance of disease.

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