The enzyme Thrombin is involved in the blood clotting cascade and cleaves the protein fibrinogen between the residues R - G to form insoluble fibrin, which allows for solid clots to form. It uses a histidine, serine and aspartic acid to do its catalytic duty, similar to how chymotrypsin works. Give a mechanism for how Thrombin works to cleave polypeptides.

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13-06-2024
Biology

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The enzyme Thrombin is involved in the blood clotting cascade and cleaves the protein fibrinogen between the residues R - G to form insoluble fibrin, which allows for solid clots to form. It uses a histidine, serine and aspartic acid to do its catalytic duty, similar to how chymotrypsin works. Give a mechanism for how Thrombin works to cleave polypeptides.

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