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A nurse is reviewing information for several clients on the unit. The nurse should recognize which of the following clients is at greatest risk for respiratory depression.
1. A client who has chronic pain and recently started taking paroxetine
2. A client who has cancer and has taken oxycodone PRN for several months
3. A client who has been accidentally taking twice the amount of prednisone as prescribed
4. A client who had surgery 3ℎ ago and is receiving IV hydromorphone PRN

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