Ms. Y is a 31-year-old woman who reported to her physician that she has recently lost
weight, always seems tired, and has experienced night sweats. A few months ago, she had
noticed a small firm lump on her neck that was painless and not tender, so she ignored it.
Closer physical examination revealed a swelling of several lymph nodes in the neck and
throat region. A blood test indicated a decreased lymphocyte count and a lymph node
biopsy revealed the presence of Reed-Sternberg cells, confirming the diagnosis of
Hodgkin’s lymphoma.