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The profoundly elevated blood pressure observed in people using cocaine is caused by:
A. a reflex and the counterbalancing parasympathetic response leads to generalized vascular constriction and vascular resistance resulting in the high blood pressure.
B. The enhanced sympathetic stimulation which leads to increased heart rate and strength of contraction, resulting in increased
C. Cardiac output and high blood pressure.
D. Its direct effect on vascular smooth cells causes them to contract, thus causing the elevated blood pressure.

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