Hepatocytes engage in the biosynthesis of a number of different molecules, including fatty acids (fatty acid synthesis) and glucose (gluconeogenesis). Which of the following statements are true of both fatty acid synthesis and gluconeogenesis? (Select two answers)
A. Certain enzymes in both pathways are allosterically regulated
B. Glucagon signaling inhibits both pathways in hepatocytes
C. Insulin signaling activates both pathways in hepatocytes
D. Acetyl-CoA is a reactant in both of these pathways
E. The net AG of both pathways is negative.