Get reliable answers to your questions at Westonci.ca, where our knowledgeable community is always ready to help. Join our platform to connect with experts ready to provide detailed answers to your questions in various areas. Get precise and detailed answers to your questions from a knowledgeable community of experts on our Q&A platform.
LDL Cholesterol in Humans + Statin. Path model: dose of drug= .03(g/d)/1 (mg/d) increases rate of transport of cholrsterol into liver cells = .95(g/d)/1(g/d) increases rate at which enzymes in the liver convert cholesterol to bile salts = -302(mg/dl)/1(g/d) decreases concentration of LDL cholesterol in the blood. What drug dosage (mg/d) must be administered to reduce the concentration of LDL cholesterol in the blood by 60 mg/dL? Note: the drug has no effect on LDL cholesterol in the body at dosages of 4.0 mg/d or less, so be sure to add 4.0 mg/d to your final answer no matter what. Hint: this question requires multiple steps. First, you need to deterkine the change in enzyme activity needed to reduce LDL cholesterol. Then, determine the change in cholesterol trasnpirt rate needed to achieve the change in enzmye activity.
