When wound edges are far apart, secondary union occurs, leading to slower wound healing. Edema and granulation tissue formation are part of the inflammatory and repair processes.
When wound edges are far apart, the process known as secondary union occurs. In this type of wound healing, the edges of the wound are pulled together through wound contraction, leading to a slower refill of cells and collagen compared to primary union wounds.
During the inflammatory phase, capillaries remain dilated causing edema and neutrophils are recruited to the area to combat pathogens. The accumulation of neutrophils, dead cells, and tissue fluids can lead to the formation of pus, which is eventually cleared out by macrophages.
Granulation tissue forms as part of the vascularization of new tissue, aiding in wound repair. When wound edges are close together, primary union allows for quicker and more thorough healing compared to secondary union wounds.
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