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A patient's grandmother developed severe nutritional deficiencies during the Great Depression. The patient currently struggles with being overweight. How might the grandmother's history contribute to the patient's condition?
A. The grandmother's nutritional deficiencies led to genetic mutations passed down to the patient, causing weight issues. The patient's condition is entirely due to their own lifestyle choices and is unrelated to the grandmother's nutritional history.
B. Nutritional deficiencies in the grandmother caused a permanent change in the family's DNA, affecting all subsequent generations.
C. The grandmother's nutritional deficiencies directly altered her DNA sequence, which was inherited by the patient.
D. Epigenetic changes due to the grandmother's nutritional deficiencies may have influenced the patient's gene expression, such as the desire to eat.

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