Final answer:
Human growth hormone (HGH) misuse in sports can lead to serious health issues such as an enlarged heart, organ tumors, and hypertension.
Explanation:
A negative effect of using human growth hormone (HGH) as a performance-enhancing drug is an enlarged heart. The misuse of HGH can lead to cardiac issues as it alters testosterone levels, posing risks of heart damage, cardiac arrhythmias, and heart failure.
Additionally, HGH abuse can result in organ tumors and hypertension, further highlighting the detrimental impact it can have on an individual's health.
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