isabella292008
Answered

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If an error in transcription causes the last cytosine in an mRNA sequence that was supposed to read UUG AUC CAA UGC to be replaced with a guanine, which of the following do you predict would happen?

A. Nothing will happen, since the last codon will still correspond to threonine.
B. Only three amino acids will be produced instead of four.
C. The first amino acid in the chain will be glycine instead of arginine.
D. The last amino acid in the chain will be tryptophan instead of cysteine.

Sagot :

GinnyAnswer
Let's analyze the question step-by-step to understand the impact of the transcription error.

1. Original mRNA Sequence and Translation:
- The original mRNA sequence is: UUG AUC CAA UGC
- We need to translate each codon in this sequence into its corresponding amino acid using the provided codon table.

[tex]\[ \begin{aligned} &\text{Codon} && \text{Amino Acid} \\ &\text{UUG} && \text{Leucine} \\ &\text{AUC} && \text{Isoleucine} \\ &\text{CAA} && \text{Glutamine} \\ &\text{UGC} && \text{Cysteine} \\ \end{aligned} \][/tex]

Therefore, the original sequence translates to: Leucine, Isoleucine, Glutamine, Cysteine.

2. Mutated mRNA Sequence and Translation:
- According to the question, an error causes the last cytosine in the sequence to be replaced with a guanine.
- The mutated mRNA sequence is: UUG AUC CAA UGG
- We need to translate this mutated sequence into its corresponding amino acids using the provided codon table.

[tex]\[ \begin{aligned} &\text{Codon} && \text{Amino Acid} \\ &\text{UUG} && \text{Leucine} \\ &\text{AUC} && \text{Isoleucine} \\ &\text{CAA} && \text{Glutamine} \\ &\text{UGG} && \text{Tryptophan} \\ \end{aligned} \][/tex]

Therefore, the mutated sequence translates to: Leucine, Isoleucine, Glutamine, Tryptophan.

3. Prediction Analysis:
- Let's evaluate the predictions provided in the question based on the given analysis:
- Nothing will happen, since the last codon will still correspond to threonine.
- This statement is incorrect because the last codon in the original sequence translates to Cysteine, not Threonine.
- Only three amino acids will be produced instead of four.
- This statement is incorrect because all four amino acids are still produced, but the last one changes.
- The first amino acid in the chain will be glycine instead of arginine.
- This statement is incorrect because the first amino acid remains Leucine.
- The last amino acid in the chain will be tryptophan instead of cysteine.
- This statement is correct because the mutation changes the last codon from UGC (Cysteine) to UGG (Tryptophan).

Hence, the correct prediction is:
The last amino acid in the chain will be tryptophan instead of cysteine.
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