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Collagen is a protein that forms part of the extracellular matrix. How would you expect it to be synthesized and trafficked outside the cell?
a. The DNA would leave the cell, where it would then make the collagen
b. It would be made at the rough ER. From there it would go to the golgi apparatus. The golgi would send it to the cell membrane in a vesicle, which would allow it to be exported.
c. The protein would be made in the nucleus. Once it's made it would make its way to a lysosome. The lysosome would help it leave the cell.
d. The ribosomes in the cytosol would make collagen. The collagen would then pass through the cell membrane to leave the cell where it is needed.

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