Answered

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n normal thyroid physiology, which of the following represents the correct feedback loop?
A. Hypothalamic thyroid-releasing hormone inhibits TSH release from the anterior pituitary → thyroid cell atrophy → reduced synthesis of T4 and T3 → decreased TSH
B. Hypothalamic thyroid-releasing hormone stimulates continuous TSH release from the anterior pituitary → thyroid cell growth → synthesis of T4 and T3 → increased TSH
C. Hypothalamic thyroid-releasing hormone triggers the pulsatile release of TSH from the anterior pituitary → thyroid cell growth → synthesis of T4 and T3→ reduced TSH
D. Hypothalamic thyroid-releasing hormone has no direct effect on TSH release from the anterior pituitary → enhanced synthesis of T4 and T3→ increased TSH

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