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Match the changed nucleotide sequences to the mutations that cause them.

Original Nucleotide Sequence: CATTCACACA

\begin{tabular}{|l|l|l|}
\hline Type of Mutation & \begin{tabular}{c}
Original Nucleotide \\
Sequence
\end{tabular} & \begin{tabular}{c}
Changed Nucleotide \\
Sequence
\end{tabular} \\
\hline deletion & CATTCACACA & CATTCACG \\
\hline insertion & CATTCACACA & CATTCACACCACG \\
\hline inversion & CATTCACACA & CATTGCACAC \\
\hline duplication & CATTCACACA & CATTCACACAC \\
\hline substitution & CATTCACACA & CATTTCACACG \\
\hline
\end{tabular}

Sagot :

Certainly! Let's go through each type of mutation and identify the corresponding changed nucleotide sequence.

1. Deletion: A deletion mutation involves the removal of one or more nucleotides from the DNA sequence. Given the original sequence is "CATTCACACG", the changed sequence with a deletion should have fewer nucleotides. The sequence "CATTCACG" fits because "CAC" has been removed.

2. Insertion: An insertion mutation involves the addition of one or more nucleotides into the DNA sequence. Among the given sequences, "CATTCACACCACG" is longer than the original "CATTCACACG", indicating additional nucleotides ("ACC") have been inserted.

3. Inversion: An inversion mutation involves a segment of the DNA sequence being reversed end to end. The sequence "CATTGCACAC" suggests that a portion of the original sequence has been inverted. Here, "GCAC" is swapped in place of "ACAC".

4. Duplication: A duplication mutation involves a segment of the DNA sequence being copied and inserted back into the genome. The sequence "CATTCACACA" shows added "CA", which is a duplication of part of the original segment "ACAC".

5. Substitution: A substitution mutation involves replacing one nucleotide with another. The sequence "CATTTCACACG" has replaced "C" with "T" in the second position after "CATT".

Let's fill out the table accordingly:

\begin{tabular}{|l|c|c|}
\hline
Type of Mutation & \begin{tabular}{c}
Original Nucleotide \\
Sequence
\end{tabular} & \begin{tabular}{c}
Changed Nucleotide \\
Sequence
\end{tabular} \\
\hline
deletion & CATTCACACG & CATTCACG \\
\hline
insertion & CATTCACACG & CATTCACACCACG \\
\hline
inversion & CATTCACACG & CATTGCACAC \\
\hline
duplication & CATTCACACG & CATTCACACA \\
\hline
substitution & CATTCACACG & CATTTCACACG \\
\hline
\end{tabular}