The dissociation constant (KD) of the drug bindamab for its receptor alpha bindin is 0.005. The drug neomab has a KD of 0.1. Which of the following is true?
A. KD is measured in both cases at equilibrium conditions
B. KD represents a ratio of bindamab to alpha binding of 0.005 (0.5%)
C. Neomab has a higher affinity for the alpha bindin receptor than bindamab
D. Doubling the amount of bindamab while keeping alpha bindin concentrations the same will increase KD to 0.01
E. The rate constants of the forward and reverse reactions (association and dissociation rate constants) are equal1.

Question

12-07-2024
Chemistry

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The dissociation constant (KD) of the drug bindamab for its receptor alpha bindin is 0.005. The drug neomab has a KD of 0.1. Which of the following is true?
A. KD is measured in both cases at equilibrium conditions
B. KD represents a ratio of bindamab to alpha binding of 0.005 (0.5%)
C. Neomab has a higher affinity for the alpha bindin receptor than bindamab
D. Doubling the amount of bindamab while keeping alpha bindin concentrations the same will increase KD to 0.01
E. The rate constants of the forward and reverse reactions (association and dissociation rate constants) are equal1.

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