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A nucleotide analog works by:

A. Stopping the formation of ergosterol in fungi.
B. Being placed into the viral genome and then stopping DNA synthesis.
C. Stopping the formation of the fungal cell wall.
D. Stopping the formation of the bacterial cell membrane.
E. Creating porins in the viral envelope.

Sagot :

GinnyAnswer

Final answer:

Nucleotide analogs inhibit viral DNA synthesis, antifungal drugs disrupt ergosterol in fungal cell membranes and cell walls, achieving selective toxicity.


Explanation:

Nucleotide Analog Mechanism of Action in Antiviral Agents

Nucleotide analogs work by being inserted into the viral genome and stopping DNA synthesis. These analogs interfere with the normal process of DNA replication by halting the addition of new nucleotides, inhibiting viral proliferation.

Additionally, antifungal drugs can target ergosterol in fungal cell membranes, disrupting the structural integrity, or fungal cell walls, affecting essential components for fungal survival.

Selective toxicity is achieved by the preference of viral polymerases to incorporate nucleotide analogs over host cell polymerases, making them effective against viral infections.


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