Inherited mutations come from one or both
this mutation,
Phenylketonuria (PKU)
the cells in the
Breast Cancer
via the gamete. Because the zygote has
will have this mutation.
Cystic Fibrosis
PKU is caused by a
in
the PAH gene, which codes for the
Some of the genes that contribute to Cystic fibrosis is caused by a
breast cancer, such as BRCA1 and
in the
that breaks down the
phenylalanine.
BRCA2, show heredity inheritance in
an
CFTR gene, which codes for a
transport protein. Like PKU,
PKU is an autosomal recessive
pattern. A
cystic fibrosis is inherited in
condition; in other words, a child may person's chance of developing breast
an
be affected only if the child inherits
cancer can
by
inheriting just
copy of the
pattern.
copies of the defective gene,
one from
Somatic Mutations
mutated gene from either parent.
I
Somatic cells are the cells that make up the
Mutations in these cells are called
of an organism. They do
divide to form gametes.
Somatic mutations are not present
from birth. They are
Somatic mutations do
through exposure to
exist in all the cells of the body. Only the
cells of
the first mutated cell will have the mutation. Somatic mutations are
passed on to offspring.