Pharmacokinetics in pregnant patients can be influenced by changes in metabolism and distribution of drugs due to physiological changes during pregnancy.
Pharmacokinetics refers to the processes a drug undergoes in the body, including absorption, distribution, metabolism, and excretion. When a patient is pregnant, these processes can be altered due to physiological changes, such as increased blood volume, altered enzyme activity, and changes in organ function.
For a pregnant patient, metabolism of drugs may be affected. For example, the activity of liver enzymes responsible for drug breakdown can change during pregnancy, potentially leading to altered drug levels in the body. This can impact the efficacy and safety of medications taken by pregnant individuals.
Furthermore, distribution of drugs may also be influenced by pregnancy-related changes in body composition and blood flow. These alterations can affect how drugs are distributed to different tissues and organs, potentially impacting the dosage and frequency of medication administration for pregnant patients.
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