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Sagot :
Vaccine contain weaakened or inactive parts of the organism or antigen. It triggers the immune response of the body. If there is a mutation that caused the pretein spike to change, the effectiveness of an original vaccination will be affected. The antibodies from the vaccine are dire3cted against it and will no longer be effective and binding to destroy the virus. This will eventually escape immune surveillance. When there is a new variant, the original vaccination will not be effective completely. But somehow, it can provide at least some protection against the new virus variant. It will not make the original vaccination totally ineffective because it will still provide an elicit immune responce. It is possible to change the composition of the vaccine to provide protection against the new variants.
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