The experience of stress is created by physiological changes through the HPA axis which consists of the Hypothalamus, Pituitary Gland, and Adrenal Glands
The hypothalamic-pituitary-adrenal axis, or HPA axis, is a term used to represent the interaction between the hypothalamus, pituitary gland, and adrenal glands; it plays an important role the body's response to stress. The pathway of the axis results in the production of cortisol. Repeated HPA axis activation has been linked to type 2 diabetes, obesity, and cardiovascular disease. Cortisol has also been demonstrated to have detrimental effects on memory and cognition, and high cortisol levels are implicated in mood disorders like depression.
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